(S)-3-amino-2-metilpropionat transaminaza
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| (S)-3-amino-2-metilpropionat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.22 | ||||||||
| CAS broj | 9031-95-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
(S)-3-amino-2-metilpropionat transaminaza (EC 2.6.1.22, L-3-aminoizobutiratna transaminaza, beta-aminobutirna transaminaza, L-3-aminoizobutirna aminotransferaza, beta-aminoizobutirat-alfa-ketoglutaratna transaminaza) je enzim sa sistematskim imenom (S)-3-amino-2-metilpropanoat:2-oksoglutarat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (S)-3-amino-2-metilpropanoat + 2-oksoglutarat 2-metil-3-oksopropanoat + L-glutamat
Ovaj enzim takođe deluje na beta-alanin i druge omega-aminokiseline sa lancima dugim 2 do 5 ugljenika.
Reference[uredi | uredi kod]
- ↑ Kakimoto, Y., Kanazawa, A., Taniguchi, K. and Sano, I. (1968). „β-Aminoisobutyrate-α-ketoglutarate transaminase in relation to β-aminoisobutyric aciduria”. Biochim. Biophys. Acta 156: 374-380. PMID 5641913.
- ↑ Tamaki, N., Sakata, S.F. and Matsuda, K. (2000). „Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver”. Methods Enzymol. 324: 376-389. PMID 10989446.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.