(Acetil-KoA karboksilaza) kinaza
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| (acetil-KoA karboksilaza) kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.11.27 | ||||||||
| CAS broj | 77000-06-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(acetil-KoA karboksilaza) kinaza (EC 2.7.11.27, acetil koenzim A karboksilaza kinaza (fosforilacija), acetil-KoA karboksilaza vezana kinaza, acetil-KoA karboksilazna kinaza, acetil-KoA karboksilazna kinaza (cAMP-nezavisna), acetil-KoA karboksilazna kinaza 2, acetil-KoA karboksilazna kinaza-2, acetil-KoA karboksilazna kinaza-3 (AMP-activated), acetil-koenzim A karboksilazna kinaza, ACK2, ACK3, AMPK, I-peptid kinaza, STK5) je enzim sa sistematskim imenom ATP:(acetil-KoA karboksilaza) fosfotransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim fosforiliše i inaktivira EC 6.4.1.2, acetil-KoA karboksilazu.
Reference[uredi | uredi kod]
- ↑ Jamil, H. and Madsen, N.B. (1987). „Phosphorylation state of acetyl-coenzyme A carboxylase. I. Linear inverse relationship to activity ratios at different citrate concentrations”. J. Biol. Chem. 262: 630-637. PMID 2879833.
- ↑ Lent, B. and Kim, K.H. (1982). „Purification and properties of a kinase which phosphorylates and inactivates acetyl-CoA carboxylase”. J. Biol. Chem. 257: 1897-1901. PMID 6120170.
- ↑ Munday, M.R. and Hardie, D.G. (1984). „Isolation of three cyclic-AMP-independent acetyl-CoA carboxylase kinases from lactating rat mammary gland and characterization of their effects on enzyme activity”. Eur. J. Biochem. 141: 617-627. PMID 6146523.
- ↑ Mohamed, A.H., Huang, W.Y., Huang, W., Venkatachalam, K.V. and Wakil, S.J. (1994). „Isolation and characterization of a novel acetyl-CoA carboxylase kinase from rat liver”. J. Biol. Chem. 269: 6859-6865. PMID 7907095.
- ↑ Heesom, K.J., Moule, S.K. and Denton, R.M. (1998). „Purification and characterisation of an insulin-stimulated protein-serine kinase which phosphorylates acetyl-CoA carboxylase”. FEBS Lett. 422: 43-46. PMID 9475166.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.