Diatrizoinska kiselina

Izvor: Wikipedia
Diatrizoinska kiselina
Diatrizoic acid.svg
Diatrizoic-acid-3D-spacefill.png
IUPAC ime
Identifikacija
CAS registarski broj 737-31-5 YesY
PubChem[1][2] 2140
ChemSpider[3] 2055 YesY
DrugBank DB00271
KEGG[4] D02240
ChEBI 53691
ChEMBL[5] CHEMBL1201220 YesY
ATC code V08AA01
Jmol-3D slike Slika 1
Slika 2
Svojstva
Molekulska formula C11H9I3N2O4
Molarna masa 613.91 g mol−1

 YesY (šta je ovo?)   (verifikuj)

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

Diatrizoinska kiselina (ili u anjonskom obliku diatrizoat), takođe poznata kao amidotrizojeva kiselina, ili 3,5-diacetamido-2,4,6-trijodobenzojeva kiselina, je radiokontrastni agens koji sadrži jod. Neka od prodajnih imena su: Hypaque, Gastrografin i Urografin (kombinacija soli natrijuma i meglumina).

Diatrizoat se smatra visoko-osmolalitskim kontrastnim agensom. Njegov osmolalitet je u opsegu od oko 1500 mOsm/kg (50% rastvor)[6] do preko 2000 mOsm/kg (76% rastvor).[7]

Reference[uredi - уреди]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. doi:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. doi:10.1093/nar/gkr777. PMID 21948594.  edit
  6. Amersham Health (April 2006). "Hypaque sodium (Diatrizoate Sodium) injection, solution. Product label". DailyMed. U.S. National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/fdaDrugXsl.cfm?id=1808&type=display. pristupljeno 29. 3. 2007.. 
  7. Amersham Health (April 2006). "Hypaque (Diatrizoate Meglumine and Diatrizoate Sodium) injection, solution. Product label". DailyMed. U.S. National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/fdaDrugXsl.cfm?id=997&type=display. pristupljeno 29. 3. 2007.. 

Spoljašnje veze[uredi - уреди]

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