2,3-Dihidroksibenzojeva kiselina

2,3-Dihidroksibenzojeva kiselina
	2,3-Dihidroksibenzojeva kiselina
Drugi nazivi	Hipogalinska kiselina; 2-Pirokatehuinska kiselina; o-Pirokatehuinska kiselina
Identifikacija
Abrevijacija	2,3-DHBA; 2,3-DHB
CAS registarski broj	303-38-8
PubChem	19
ChemSpider	18
DrugBank	DB01672
KEGG	C00196
ChEMBL	CHEMBL1432
Jmol-3D slike	Slika 1; Slika 2
SMILES
	O=C(O)c1cccc(O)c1O c1cc(c(c(c1)O)O)C(=O)O
InChI
	InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11) ; Kod: GLDQAMYCGOIJDV-UHFFFAOYSA-N InChI=1/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11); Kod: GLDQAMYCGOIJDV-UHFFFAOYAE
Svojstva
Molekulska formula	C7H6O4
Molarna masa	154.12 g mol−1
Agregatno stanje	Bezbojna tečnost
Tačka topljenja	204-206 °C, 477-479 K, 399-403 °F
Rastvorljivost u vodi	niska
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

2,3-Dihidroksibenzojeva kiselina je prirodni fenol prisutan u Phyllanthus acidus^[6] i u vodenoj paprati Salvinia molesta.^[7]

2,3-Dihidroksibenzojeva kiselina je takođe produkt ljudskog metabolizma aspirina.^[8]

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Sousa M, Ousingsawat J, Seitz R, et al. (January 2007). „An extract from the medicinal plant Phyllanthus acidus and its isolated compounds induce airway chloride secretion: A potential treatment for cystic fibrosis”. Mol. Pharmacol. 71 (1): 366–76. DOI:10.1124/mol.106.025262. PMID 17065237.
↑ Choudhary, M. I.; Naheed, N.; Abbaskhan, A.; Musharraf, S. G.; Siddiqui, H.; Atta-Ur-Rahman (2008). „Phenolic and other constituents of fresh water fern Salvinia molesta”. Phytochemistry 69 (4): 1018–1023. DOI:10.1016/j.phytochem.2007.10.028. PMID 18177906.
↑ Grootveld, M.; Halliwell, B. (1988). „2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism”. Biochemical Pharmacology 37 (2): 271–280. DOI:10.1016/0006-2952(88)90729-0. PMID 3342084.

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[6] Sousa M, Ousingsawat J, Seitz R, et al. (January 2007). „An extract from the medicinal plant Phyllanthus acidus and its isolated compounds induce airway chloride secretion: A potential treatment for cystic fibrosis”. Mol. Pharmacol. 71 (1): 366–76. DOI:10.1124/mol.106.025262. PMID 17065237.

[7] Choudhary, M. I.; Naheed, N.; Abbaskhan, A.; Musharraf, S. G.; Siddiqui, H.; Atta-Ur-Rahman (2008). „Phenolic and other constituents of fresh water fern Salvinia molesta”. Phytochemistry 69 (4): 1018–1023. DOI:10.1016/j.phytochem.2007.10.028. PMID 18177906.

[8] Grootveld, M.; Halliwell, B. (1988). „2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism”. Biochemical Pharmacology 37 (2): 271–280. DOI:10.1016/0006-2952(88)90729-0. PMID 3342084.

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2,3-Dihidroksibenzojeva kiselina

Reference[uredi | uredi kod]

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