Undekaprenil-fosfat 4-dezoksi-4-formamido-L-arabinoza transferaza
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Undekaprenil-fosfat 4-dezoksi-4-formamido-L-arabinoza transferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.8.30 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Undekaprenil-fosfat 4-dezoksi-4-formamido-L-arabinoza transferaza (EC 2.7.8.30, undekaprenil-fosfat Ara4FN transferaza, Ara4FN transferaza, protein polimiksinske otpornosti PmrF, UDP-4-amino-4-dezoksi-alfa-L-arabinoza:ditrans,policis-undekaprenil fosfat 4-amino-4-dezoksi-alfa-L-arabinoziltransferaza) je enzim sa sistematskim imenom UDP-4-amino-4-dezoksi-alfa-L-arabinoza:ditrans,oktacis-undekaprenil fosfat 4-amino-4-dezoksi-alfa-L-arabinosiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-4-dezoksi-4-formamido-beta-L-arabinopiranoza + ditrans,oktacis-undekaprenil fosfat UDP + 4-dezoksi-4-formamido-alfa-L-arabinopiranozil ditrans,oktacis-undekaprenil fosfat
Ovaj enzim nije aktivan sa UDP-4-amino-4-dezoksi-beta-L-arabinozom.
- ↑ Breazeale, S.D., Ribeiro, A.A. and Raetz, C.R. (2002). „Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose”. J. Biol. Chem. 277: 2886-2896. PMID 11706007.
- ↑ Breazeale, S.D., Ribeiro, A.A., McClerren, A.L. and Raetz, C.R.H. (2005). „A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-amino-4-deoxy-L-arabinose. Identification and function of UDP-4-deoxy-4-formamido-L-arabinose”. J. Biol. Chem. 280: 14154-14167. PMID 15695810.
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