Arsenat reduktaza (citohrom c)
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Arsenat reduktaza (citohrom c) | |||||||||
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Identifikatori | |||||||||
EC broj | 1.20.2.1 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Arsenat reduktaza (citohrom c) (EC 1.20.2.1, arsenitna oksidaza) je enzim sa sistematskim imenom arsenit:citohrom c oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- arsenit + H2O + 2 oksidovani citohrom c arsenat + 2 redukovani citohrom c + 2 H+
Ovaj molibdoprotein sadrži gvožđe-sumporne klastere. On je izolovan iz alfa-proteobakterija.
Reference[uredi | uredi kod]
- ↑ vanden Hoven, R.N. and Santini, J.M. (2004). „Arsenite oxidation by the heterotroph Hydrogenophaga sp. str. NT-14: the arsenite oxidase and its physiological electron acceptor”. Biochim. Biophys. Acta 1656: 148-155. PMID 15178476.
- ↑ Santini, J.M., Kappler, U., Ward, S.A., Honeychurch, M.J., vanden Hoven, R.N. and Bernhardt, P.V. (2007). „The NT-26 cytochrome c552 and its role in arsenite oxidation”. Biochim. Biophys. Acta 1767: 189-196. PMID 17306216.
- ↑ Branco, R., Francisco, R., Chung, A.P. and Morais, P.V. (2009). „Identification of an aox system that requires cytochrome c in the highly arsenic-resistant bacterium Ochrobactrum tritici SCII24”. Appl. Environ. Microbiol. 75: 5141-5147. PMID 19525272.
- ↑ Lieutaud, A., van Lis, R., Duval, S., Capowiez, L., Muller, D., Lebrun, R., Lignon, S., Fardeau, M.L., Lett, M.C., Nitschke, W. and Schoepp-Cothenet, B. (2010). „Arsenite oxidase from Ralstonia sp. 22: characterization of the enzyme and its interaction with soluble cytochromes”. J. Biol. Chem. 285: 20433-20441. PMID 20421652.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.