(3-Metil-2-oksobutanoat dehidrogenaza (2-metilpropanoil-transferprsten))-fosfataza
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(3-Metil-2-oksobutanoat dehidrogenaza (2-metilpropanoil-transferprsten))-fosfataza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.1.3.52 | ||||||||
CAS broj | 88086-29-7&title= 87244-20-0, 88086-29-7 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(3-Metil-2-oksobutanoat dehidrogenaza (2-metilpropanoil-transferprsten))-fosfataza (EC 3.1.3.52, dehidrogenazna fosfataza okso-kiselina razgranatog lanca, dehidrogenaza fosfataza 2-keto kiselina razgranatog lanca, dehidrogenaza fosfataza alfa-keto kiselina razgranatog lanca, BCKDH, (3-metil-2-oksobutanoat dehidrogenaza (lipoamid))-fosfataza, (3-metil-2-oksobutanoat dehidrogenaza (lipoamid))-fosfat fosfohidrolaza) je enzim sa sistematskim imenom (3-metil-2-oksobutanoat dehidrogenaza (2-metilpropanoil-transfer))-fosfat fosfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- [3-metil-2-oksobutanoat dehidrogenaza (2-metilpropanoil-transfer)] fosfat + H2O [3-metil-2-oksobutanoat dehidrogenaza (2-metilpropanoil-transfer)] + fosfat
Ovaj mitohondrijski enzim je u kompleksu sa 3-metil-2-oksobutanoat dehidrogenazom.
- ↑ Fatania, H.R., Patston, P.A. and Randle, P.J. (1983). „Dephosphorylation and reactivation of phosphorylated purified ox-kidney branched-chain dehydrogenase complex by co-purified phosphatase”. FEBS Lett. 158: 234-238. PMID 6307746.
- ↑ Reed, L.J., Damuni, Z. and Merryfield, M.L. (1985). „Regulation of mammalian pyruvate and branched-chain α-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation”. Curr. Top. Cell. Regul. 27: 41-49. PMID 3004826.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.