Nikotianamin

Nikotianamin
	N-(N-(3-amino-3-karboksipropil)-3-amino-3-karboksipropil)azetidin-2-karboksilna kiselina
Identifikacija
CAS registarski broj	34441-14-0
PubChem	7705
ChemSpider	8058557
Jmol-3D slike	Slika 1
SMILES
	C1CN([C@@H]1C(=O)O)CC[C@@H](C(=O)O)NCC[C@@H](C(=O)O)N
Svojstva
Molekulska formula	C12H21N3O6
Molarna masa	303,31164 g/mol
	; ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Nikotianamin je inhibitor angiotenzin I-konvertujućeg enzima. On je metal-helirajući molekul, koji je sveprisutan kod viših biljki.^[4] Biohemijski ovo jedinjenje sintetiše enzim nikotianaminska sintaza, koja koristi tri molekula S-adenozilmetionina.^[5]

References[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Takahashi M, Terada Y, Nakai I, Nakanishi H, Yoshimura E, Mori S, Nishizawa NK. (2003). „Role of nicotianamine in the intracellular delivery of metals and plant reproductive development”. The Plant Cell 15 (6): 1263–80.
↑ Zheng L, Cheng Z, Ai C, Jiang X, Bei X, Zheng Y, Glahn RP, Welch RM, Miller DD, Lei XG, Shou H. (2010). „Nicotianamine, a novel enhancer of rice iron bioavailability to humans”. PLOS 5 (4): e10190. DOI:10.1371/journal.pone.0010190.

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