Hromatidni kohezioni protein 1
Kohezinski kompleks se sastoji od[1]
Identifikatori
Simbol
MCD1
Alt. simboli
PDS3, RHC21, SCC1
Entrez
851561
PDB
1W1W
UniProt
Q12158
Drugi podaci
Strukturno održavanje hromozomskog proteina 3
Identifikatori
Simbol
SMC3
Alt. simboli
J1049
Entrez
853371
UniProt
P47037
Drugi podaci
Kohesin je proteinski kompleks koji reguliše separaciju hromatida tokom ćelijske deobe, bilo mitoze ili mejoze .[2] [3] [4]
↑ PDB 1W1W ; Haering CH, Schoffnegger D, Nishino T, Helmhart W, Nasmyth K, Löwe J (September 2004). „Structure and stability of cohesin's Smc1-kleisin interaction”. Mol. Cell 15 (6): 951–64. DOI :10.1016/j.molcel.2004.08.030 . PMID 15383284 . ↑ Michaelis C, Ciosk R, Nasmyth K (October 1997). „Cohesins: chromosomal proteins that prevent premature separation of sister chromatids”. Cell 91 (1): 35–45. DOI :10.1016/S0092-8674(01)80007-6 . PMID 9335333 . ↑ Guacci V, Koshland D, Strunnikov A (October 1997). „A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae” . Cell 91 (1): 47–57. DOI :10.1016/S0092-8674(01)80008-8 . PMC 2670185 . PMID 9335334 . ↑ Tóth A, Ciosk R, Uhlmann F, Galova M, Schleiffer A, Nasmyth K (February 1999). „Yeast Cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication” . Genes Dev. 13 (3): 320–33. DOI :10.1101/gad.13.3.320 . PMC 316435 . PMID 9990856 .
Michaelis C, Ciosk R, Nasmyth K (October 1997). „Cohesins: chromosomal proteins that prevent premature separation of sister chromatids”. Cell 91 (1): 35–45. DOI :10.1016/S0092-8674(01)80007-6 . PMID 9335333 . Guacci V, Koshland D, Strunnikov A (October 1997). „A Direct Link between Sister Chromatid Cohesion and Chromosome Condensation Revealed through the Analysis of MCD1 in S. cerevisiae” . Cell 91 (1): 47–57. DOI :10.1016/S0092-8674(01)80008-8 . PMC 2670185 . PMID 9335334 . Tóth A, Ciosk R, Uhlmann F, Galova M, Schleiffer A, Nasmyth K (February 1999). „Yeast Cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication” . Genes Dev. 13 (3): 320–33. DOI :10.1101/gad.13.3.320 . PMC 316435 . PMID 9990856 . Uhlmann F, Lottspeich F, Nasmyth K (July 1999). „Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1”. Nature 400 (6739): 37–42. DOI :10.1038/21831 . PMID 10403247 .
