Geosminska sintaza

Izvor: Wikipedia
Geosminska sintaza
Geosminsynthase2.png
Identifikatori
EC broj 4.1.99.16
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Geosminska sintaza (EC 4.1.99.16) je enzim sa sistematskim imenom germakradienol geosmin-lijaza (formira aceton).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

(1E,4S,5E,7R)-germakra-1(10),5-dien-11-ol + H2O \rightleftharpoons (-)-geosmin + aceton

Za dejstvo ovog enzima je neophodan jon Mg2+.

Reference[uredi - уреди]

  1. Jiang, J., He, X. and Cane, D.E. (2006). "Geosmin biosynthesis. Streptomyces coelicolor germacradienol/germacrene D synthase converts farnesyl diphosphate to geosmin". J. Am. Chem. Soc. 128: 8128–8129. PMID 16787064. 
  2. Cane, D.E., He, X., Kobayashi, S., Omura, S. and Ikeda, H. (2006). "Geosmin biosynthesis in Streptomyces avermitilis. Molecular cloning, expression, and mechanistic study of the germacradienol/geosmin synthase". J. Antibiot. (Tokyo) 59: 471–479. PMID 17080683. 
  3. Jiang, J., He, X. and Cane, D.E. (2007). "Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme". Nat. Chem. Biol. 3: 711–715. PMID 17873868. 

Literatura[uredi - уреди]

Spoljašnje veze[uredi - уреди]