Zn2+ eksportujuća ATPaza

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Zn2+ eksportujuća ATPaza
Identifikatori
EC broj 3.6.3.5
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Zn2+ eksportujuća ATPaza (EC 3.6.3.5, Zn(II)-translocirajuća P-tip ATPaza, P1B-tip ATPaza, AtHMA4) je enzim sa sistematskim imenom ATP fosfohidrolaza (Zn2+ eksport).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + H2O + Zn2+in ADP + fosfat + Zn2+sout

Ova P-tip ATPaza podleže kovalentnoj fosforilaciji tokom transportnog ciklusa.

Reference[uredi - уреди | uredi izvor]

  1. Beard, S.J., Hashim, R., Membrillo-Hernández, J., Hughes, M.N. and Poole, R.K. (1997). "Zinc(II) tolerance in Escherichia coli K-12: evidence that the zntA gene (o732) encodes a cation transport ATPase". Mol. Microbiol. 25: 883–891. PMID 9364914. 
  2. Rensing, C., Mitra, B. and Rosen, B.P. (1997). "The zntA gene of Escherichia coli encodes a Zn(II)-translocating P-type ATPase". Proc. Natl. Acad. Sci. USA 94: 14326–14331. PMID 9405611. 
  3. Rensing, C., Sun, Y., Mitra, B. and Rosen, B.P. (1998). "Pb(II)-translocating P-type ATPases". J. Biol. Chem. 273: 32614–32617. PMID 9830000. 
  4. Mills, R.F., Francini, A., Ferreira da Rocha, P.S., Baccarini, P.J., Aylett, M., Krijger, G.C. and Williams, L.E. (2005). "The plant P1B-type ATPase AtHMA4 transports Zn and Cd and plays a role in detoxification of transition metals supplied at elevated levels". FEBS Lett. 579: 783–791. PMID 15670847. 
  5. Eren, E. and Argüello, J.M. (2004). "Arabidopsis HMA2, a divalent heavy metal-transporting P(IB)-type ATPase, is involved in cytoplasmic Zn2+ homeostasis". Plant Physiol. 136: 3712–3723. PMID 15475410. 

Literatura[uredi - уреди | uredi izvor]

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