Vodonik:hinon oksidoreduktaza
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| Vodonik:hinon oksidoreduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.12.5.1 | ||||||||
| CAS broj | 151616-65-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Vodonik:hinon oksidoreduktaza (EC 1.12.5.1, vodonik-ubihinonska oksidoreduktaza, vodonik:menahinon oksidoreduktaza, hidrogenaza vezana za membranu, hinon-reaktivna Ni/Fe-hidrogenaza) je enzim sa sistematskim imenom vodonik:hinon oksidoreduktaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- H2 + menahinon menahinol
Ovaj enzim sadrži nikal, gvožđe-sumporne klustere i citohrom b. On takođe katalizuje redukciju u vodi rastvornih hinona (e.g. 2,3-dimetilnaftohinona) ili viologen boja (benzil viologen ili metil viologen).
Reference[uredi | uredi kod]
- ↑ Dross, F., Geisler, V., Lenger, R., Theis, F., Krafft, T., Fahrenholz, F., Kojro, E. (1992). „, Duchêne, A., Tripier, D., Juvenal, K. and Kröger, A. The quinone-reactive Ni/Fe-hydrogenase of Wolinella succinogenes”. Eur. J. Biochem. 206: 93-102. PMID 1587288.
- ↑ Dross, F., Geisler, V., Lenger, R., Theis, F., Krafft, T., Fahrenholz, F., Kojro, E., Duchene, A., Tripier, D. and Juvenal, K. (1993). „Erratum to "The quinone-reactive Ni/Fe-hydrogenase of Wolinella Succinogenes"”. Eur. J. Biochem. 214: 949-950. PMID 8319698.
- ↑ Gross, R., Simon, J., Lancaster, C.R.D. and Kroger, A. (1998). „Identification of histidine residues in Wolinella succinogenes hydrogenase that are essential for menaquinone reduction by H-2”. Mol. Microbiol. 30: 639-646. PMID 9822828.
- ↑ Bernhard, M., Benelli, B., Hochkoeppler, A., Zannoni, D. and Friedrich, B. (1997). „Functional and structural role of the cytochrome b subunit of the membrane-bound hydrogenase complex of Alcaligenes eutrophus H16”. Eur. J. Biochem. 248: 179-186. PMID 9310376.
- ↑ Ferber, D.M. and Maier, R.J. (1993). „Hydrogen-ubiquinone oxidoreductase activity by the Bradyrhizobium japonicum membrane-bound hydrogenase”. FEMS Microbiol. Lett. 110: 257-264. PMID 8354459.
- ↑ Ishii, M., Omori, T., Igarashi, Y., Adachi, O., Ameyama, M. and Kodama, T. (1991). „Methionaquinone is a direct natural electron-acceptor for the membrane-bound hydrogenase in Hydrogenobacter thermophilus strain TK-6”. Agric. Biol. Chem. 55: 3011-3016.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.