Vanilat monooksigenaza
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| Vanilat monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.82 | ||||||||
| CAS broj | 39307-11-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Vanilat monooksigenaza (EC 1.14.13.82, 4-hidroksi-3-metoksibenzoatna demetilaza, vanilatna demetilaza) je enzim sa sistematskim imenom vanilat:kiseonik oksidoreduktaza (demetilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- vanilat + O2 + NADH + H+ 3,4-dihidroksibenzoat + NAD+ + H2O + formaldehid
Ovaj enzim učestvuje u degradaciji vanilina kod Arthrobacter sp.
Reference[uredi | uredi kod]
- ↑ Brunel, F. and Davison, J. (1988). „Cloning and sequencing of Pseudomonas genes encoding vanillate demethylase”. J. Bacteriol. 170: 4924-4930. PMID 3170489.
- ↑ Priefert, H., Rabenhorst, J. and Steinbuchel, A. (1997). „Molecular characterization of genes of Pseudomonas sp. strain HR199 involved in bioconversion of vanillin to protocatechuate”. J. Bacteriol. 179: 2595-2607. PMID 9098058.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.