Triptofan—fenilpiruvat transaminaza
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| Triptofan—fenilpiruvat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.28 | ||||||||
| CAS broj | 37277-87-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Triptofan—fenilpiruvat transaminaza (EC 2.6.1.28, L-triptofan-alfa-ketoizokaproatna aminotransferaza) je enzim sa sistematskim imenom L-triptofan:fenilpiruvat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-triptofan + fenilpiruvat (indol-3-il)piruvat + L-fenilalanin
Valin, leucin i izoleucin mogu da zamene triptofan kao amino donor.
Reference[uredi | uredi kod]
- ↑ Koide, Y., Honma, M. and Shimomura, T. (1980). „L-Tryptophan-α-ketoisocaproate aminotransferase from Pseudomonas sp”. Agric. Biol. Chem. 44: 2013-2019.
- ↑ Sukanya, N.K. and Vaidyanathan, C.S. (1964). „Aminotransferases of Agrobacterium tumefaciens. Transamination between tryptophan and phenylpyruvate”. Biochem. J. 92: 594-598. PMID 5837443.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.