Transportujuća ATPaza vitamina B12
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| Transportujuća ATPaza vitamina B12 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.3.33 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Transportujuća ATPaza vitamina B12 (EC 3.6.3.33) je enzim sa sistematskim imenom ATP fosfohidrolaza (import vitamina B12).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + H2O + vitamin B12out ADP + fosfat + vitamin B12in
Ova ATPaza ABC-tipa je karakteristična po prisustvu dva slična ATP-vezujuća domena.
Reference[uredi | uredi kod]
- ↑ Kuan, G., Dassa, E., Saurin, N., Hofnung, M. and Saier, M.H., Jr. (1995). „Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases”. Res. Microbiol. 146: 271-278. PMID 7569321.
- ↑ Saier, M.H., Jr. (1998). „Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya”. Adv. Microb. Physiol. 40: 81-136. PMID 9889977.
- ↑ Friedrich, M.J., de Veaux, L.C. and Kadner, R.J. (1986). „Nucleotide sequence of the btuCED genes involved in vitamin B12 transport in Escherichia coli and homology with components of periplasmic-binding-protein-dependent transport systems”. J. Bacteriol. 167: 928-934. PMID 3528129.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.