Transportujuća ATPaza polarnih aminokiselina

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Transportujuća ATPaza polarnih aminokiselina
Identifikatori
EC broj 3.6.3.21
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Transportujuća ATPaza polarnih aminokiselina (EC 3.6.3.21, histidinska permeaza) je enzim sa sistematskim imenom ATP fosfohidrolaza (import polarne aminokiseline).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + H2O + polar amino kiselinaout ADP + fosfat + polar aminokiselinain

Ova ATPaza ABC-tipa je karakteristična po prisustvu dva slična ATP-vezujuća domena.

Reference[uredi - уреди | uredi izvor]

  1. Kuan, G., Dassa, E., Saurin, N., Hofnung, M. and Saier, M.H., Jr. (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146: 271–278. PMID 7569321. 
  2. Saier, M.H., Jr. (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. PMID 9889977. 
  3. Nikaido, K., Liu, P.Q. and Ferro-Luzzi Ames, G. (1997). "Purification and characterization of HisP, the ATP-binding subunit of a traffic ATPase (ABC transporter), the histidine permease of Salmonella typhimurium. Solubilization, dimerization , and ATPase activity". J. Biol. Chem. 272: 27745–27752. PMID 9346917. 
  4. Walshaw, D.L., Lowthorpe, S., East, A. and Poole, P.S. (1997). "Distribution of a sub-class of bacterial ABC polar amino acid transporter and identification of an N-terminal region involved in solute specificity". FEBS Lett. 414: 397–401. PMID 9315727. 

Literatura[uredi - уреди | uredi izvor]

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