Transmembranski domen ABC transportera
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| Transmembranski domen ABC transportera | |
|---|---|
| Identifikatori | |
| Simbol | ABC_membrane |
| Pfam | PF00664 |
| InterPro | IPR001140 |
| PROSITE | PDOC00364 |
| SKOP | 1pf4 |
| TCDB | 3.A.1 |
| OPM familija | Eksporteri lipida/lekova 1.1.10.03. Eksporteri lipida/lekova |
| OPM protein | 2hyd |
Transmembranski domen ABC transportera je glavna transmembranska strukturna jedinica ATP-vezujućeg kasetnog transportera koja se sastoji od šest transmembranskih domena. Mnogi članovi ABC transporterske familije (Pfam PF00005) imaju dva takva regiona.[1][2][3][4][5][6]
Potfamilije[uredi | uredi kod]
- Sulfatni ABC transporterski permeazni protein 2 IPR005667
- Fosfatni transporterski sistem, permeazni protein 2 IPR005672
- Transporter fosfonatnog preuzimanja IPR005769
- Nitratna transportna permeaza IPR005889
- NifC-slični ABC-tip porter IPR006469
- Fosfatni ABC transporter, permeazni protein PstC IPR011864
- Molibdatni ABC transporter, permeazni protein IPR011867
- Niklov ABC transporter, permeazna podjedinica NikB IPR014156
- Niklov ABC transporter, permeazna podjedinica NikC IPR014157
- Ektoin/hidroksiektoinski ABC transporter, permeazni protein EhuD IPR014341
- Ektoin/hidroksiektoinski ABC transporter, permeazni protein EhuC IPR014342
Ljudski proteini koji sadrže ovaj domen[uredi | uredi kod]
ABCB1; ABCB10; ABCB11; ABCB4; ABCB5; ABCB6; ABCB7; ABCB8; ABCB9; ABCC1; ABCC10; ABCC11; ABCC12; ABCC13; ABCC2; ABCC3; ABCC4; ABCC5; ABCC6; ABCC8; ABCC9; CFTR; TAP1; TAP2; TAPL;
Reference[uredi | uredi kod]
- ↑ Kerr ID (2002). „Structure and association of ATP-binding cassette transporter nucleotide-binding domains”. Biochim. Biophys. Acta 1561 (1): 47–64. DOI:10.1016/s0304-4157(01)00008-9. PMID 11988180.
- ↑ Hunt JF, Yuan YR, Martsinkevich O, Millen L, Thomas PJ, Karpowich N, Dai PL, MacVey K (2001). „Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter”. Structure 9 (7): 571–86. DOI:10.1016/S0969-2126(01)00617-7. PMID 11470432.
- ↑ Hunt JF, Yuan YR, Blecker S, Martsinkevich O, Millen L, Thomas PJ (2001). „The crystal structure of the MJ0796ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter”. J. Biol. Chem. 276 (34): 32313–21. DOI:10.1074/jbc.M100758200. PMID 11402022.
- ↑ Kim SH, Hung LW, Wang IX, Nikaido K, Liu PQ, Ames GF (1998). „Crystal structure of the ATP-binding subunit of an ABC transporter”. Nature 396 (6712): 703–707. DOI:10.1038/25393. PMID 9872322.
- ↑ Welte W, Breed J, Boos W, Diederichs K, Vonrhein C, Muller C, Diez J, Greller G, Schnell C (2000). „Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis”. EMBO J. 19 (22): 5951–61. DOI:10.1093/emboj/19.22.5951. PMC 305842. PMID 11080142.
- ↑ Wiley DC, Gaudet R (2001). „Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing”. EMBO J. 20 (17): 4964–72. DOI:10.1093/emboj/20.17.4964. PMC 125601. PMID 11532960.