Thermospermin sintaza
Prijeđi na navigaciju
Prijeđi na pretragu
| Thermospermin sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.79 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Thermospermin sintaza (EC 2.5.1.79, TSPMS, ACL5, SAC51) je enzim sa sistematskim imenom S-adenozilmetioninamin:spermidin 3-aminopropiltransferaza (termospermin sinteza).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozilmetioninamin + spermidin S-metil-5'-tioadenozin + termospermin + H+
Ovaj enzim je neophodan za korektnu specifikaciju ksilema, što se ostvaruje putem regulacije životnog veka ksilemskih elemenata.
Reference[uredi | uredi kod]
- ↑ Romer, P., Faltermeier, A., Mertins, V., Gedrange, T., Mai, R. and Proff, P. (2008). „Investigations about N-aminopropyl transferases probably involved in biomineralization”. J. Physiol. Pharmacol. 59 Suppl 5: 27-37. PMID 19075322.
- ↑ Knott, J.M., Romer, P. and Sumper, M. (2007). „Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine”. FEBS Lett. 581: 3081-3086. PMID 17560575.
- ↑ Muniz, L., Minguet, E.G., Singh, S.K., Pesquet, E., Vera-Sirera, F., Moreau-Courtois, C.L., Carbonell, J., Blazquez, M.A. and Tuominen, H. (2008). „ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death”. Development 135: 2573-2582. PMID 18599510.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.