Sterigmatocistin 8-O-metiltransferaza
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| Sterigmatocistin 8-O-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.110 | ||||||||
| CAS broj | 116958-29-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Sterigmatocistin 8-O-metiltransferaza (EC 2.1.1.110, sterigmatocistinska metiltransferaza, O-metiltransferaza II, sterigmatocistinska 7-O-metiltransferaza, S-adenozil-L-metionin:sterigmatocistin 7-O-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:sterigmatocistin 8-O-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + sterigmatocistin S-adenozil-L-homocistein + 8-O-metilsterigmatocistin
Dihidrosterigmatocistin takođe može da deluje kao akceptor. Ovaj enzim učestvuje u biosintezi aflatoksina kod gljiva.
Reference[uredi | uredi kod]
- ↑ Bhatnagar, D., McCormick, S.P., Lee, L.S. and Hill, R.A. (1987). „Identification of O-methylsterigmatocystin as an aflatoxin B1 and G1 precursor in Aspergillus parasiticus”. Appl. Environ. Microbiol. 53: 1028-1033. PMID 3111363.
- ↑ Yabe, K., Ando, Y., Hashimoto, J. and Hamasaki, T. (1989). „2 distinct O-methyltransferases in aflatoxin biosynthesis”. Appl. Environ. Microbiol. 55: 2172-2177. PMID 2802602.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.