Spermozin
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| Spermozin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.99 | ||||||||
| CAS broj | 89925-67-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Spermozin (EC 3.4.21.99, Spermosin) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza arginil veza, preferentrno sa Pro u P2 poziciji
Enzim iz ascidijana (Prochordate) Halocynthia roretzi je lokalizovan u glavi sperme.
Reference[uredi | uredi kod]
- ↑ Sawada, H., Yokosawa, H. and Ishii, S. (1984). „Purification and characterization of two types of trypsin-like enzymes from sperm of the ascidian (Prochordata) Halocynthia roretzi. Evidence for the presence of spermosin, a novel acrosin-like enzyme”. J. Biol. Chem. 259: 2900-2904. PMID 6365918.
- ↑ Sawada, H., Yokosawa, H., Someno, T., Saino, T. and Ishii, S. (1984). „Evidence for the participation of two sperm proteases, spermosin and acrosin, in fertilization of the ascidian, Halocynthia roretzi: inhibitory effects of leupeptin analogs on enzyme activities and fertilization”. Dev. Biol. 105: 246-249. PMID 6381175.
- ↑ Sawada, H., Iwasaki, K., Kihara-Negishi, F., Ariga, H. and Yokosawa, H. (1996). „Localization, expression, and the role in fertilization of spermosin, an ascidian sperm trypsin-like protease”. Biochem. Biophys. Res. Commun. 222: 499-504. PMID 8670234.
- ↑ Sawada, H. and Someno, T. (1996). „Substrate specificity of ascidian sperm trypsin-like proteases, spermosin and acrosin”. Mol. Reprod. Dev. 45: 240-243. PMID 8914083.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.