Spermidin dehidrogenaza
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| Spermidin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.99.6 | ||||||||
| CAS broj | 9076-64-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Spermidin dehidrogenaza (EC 1.5.99.6, spermidin:(akceptor) oksidoreduktaza) je enzim sa sistematskim imenom spermidin:akceptor oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- spermidin + akceptor + H2O propan-1,3-diamin + 4-aminobutanal + redukovani akceptor
Ovaj enzim je flavohemoprotein (FAD). Fericijanid, 2,6-dihloroindofenol i citohrom c mogu da budu akceptori.
Reference[uredi | uredi kod]
- ↑ Tabor, C.W. and Kellogg, P.D. (1970). „Identification of flavin adenine dinucleotide and heme in a homogeneous spermidine dehydrogenase from Serratia marcescens”. J. Biol. Chem. 245: 5424-5433. PMID 4918845.
- ↑ Tabor, H. and Tabor, C.W. (1972). „Biosynthesis and metabolism of 1,4-diaminobutane, spermidine, spermine, and related amines. IIE2a Speridine dehydrogenase”. Adv. Enzymol. Relat. Areas Mol. Biol. 36: 225-226.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.