Sinefrinska dehidrataza
(Preusmjereno sa stranice Sinefrin dehidrataza)
| Sinefrinska dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.88 | ||||||||
| CAS broj | 104118-54-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Sinefrinska dehidrataza (EC 4.2.1.88, siringinaza) je enzim sa sistematskim imenom (R)-sinefrin hidrolijaza (formira metilamin).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (R)-sinefrin (4-hidroksifenil)acetaldehid + metilamin
Uklanjanjem H2O sa (R)-sinefrina formira se 2,3-enamin.
Reference[uredi | uredi kod]
- ↑ Veeraswamy, M., Devi, N.A., Krishnan Kutty, R. and Subba Rao, P.V. (1976). „Conversion of (±) synephrine into p-hydroxyphenylacetaldehyde by Arthrobacter synephrinum. A novel enzymic reaction”. Biochem. J. 159: 807-809. PMID 1008837.
- ↑ Manne, V., Kutty, K.R. and Pillarisetti, S.R. (1986). „Purification and properties of synephrinase from Arthrobacter synephrinum”. Arch. Biochem. Biophys. 248: 324-334. PMID 3729420.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.