Saharopin dehidrogenaza (NAD+, formira L-lizin)
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| Saharopin dehidrogenaza (NAD+, formira L-lizin) | |||||||||
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| Saharopin dehidrogenaza (NAD+, formira L-lizin) homodimer, Saccharomyces cerevisiae | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.5.1.7 | ||||||||
| CAS broj | 9073-96-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Saharopin dehidrogenaza (NAD+, formira L-lizin) (EC 1.5.1.7, lizin-2-oksoglutarat reduktaza, dehidrogenaza, saharopin (nikotinamid adenin dinukleotid, formira lizin), epsilon-N-(L-glutaril-2)-L-lizin:NAD oksidoreduktaza (formira L-lizin), N6-(glutar-2-il)-L-lizin:NAD oksidoreduktaza (formira L-lizin), 6-N-(L-1,3-dikarboksipropil)-L-lizin:NAD+ oksidoreduktaza (formira L-lizin)) je enzim sa sistematskim imenom N6-(L-1,3-dikarboksipropil)-L-lizin:NAD+ oksidoreduktaza (formira L-lizin).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- N6-(L-1,3-dikarboksipropil)-L-lizin + NAD+ +H2O L-lizin + 2-oksoglutarat + NADH + H+
Reference[uredi | uredi kod]
- ↑ Fujioka, M. and Nakatani, Y. (1972). „Saccharopine dehydrogenase. Interaction with substrate analogues”. Eur. J. Biochem. 25: 301-307. PMID 4339117.
- ↑ Saunders, P.P. and Broquist, H.P. (1966). „Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. IV. Saccharopine dehydrogenase”. J. Biol. Chem. 241: 3435-3440. PMID 4287986.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.