S-(hidroksimetil)glutationska sintaza
(Preusmjereno sa stranice S-(hidroksimetil)glutation sintaza)
| S-(hidroksimetil)glutationska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.4.1.22 | ||||||||
| CAS broj | 425642-27-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
S-(hidroksimetil)glutationska sintaza (EC 4.4.1.22, glutation-zavisni formaldehid-aktivirajući enzim, Gfa, S-(hidroksimetil)glutation formaldehid-lijaza) je enzim sa sistematskim imenom S-(hidroksimetil)glutation formaldehid-lijaza (formira glutation).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-(hidroksimetil)glutation glutation + formaldehid
Enzim iz Paracoccus denitrificans}_ ubrzava spontanu reakciju u spajaju formaldehid i glutation.
Reference[uredi | uredi kod]
- ↑ Goenrich, M., Bartoschek, S., Hagemeier, C.H., Griesinger, C. and Vorholt, J.A. (2002). „A glutathione-dependent formaldehyde-activating enzyme (Gfa) from Paracoccus denitrificans detected and purified via two-dimensional proton exchange NMR spectroscopy”. J. Biol. Chem. 277: 3069-3072. PMID 11741920.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.