Riboflavin kinaza

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Riboflavin kinaza
PDB 1s4m EBI.jpg
Identifikatori
EC broj 2.7.1.26
CAS broj 9032-82-0
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Riboflavin kinaza (EC 2.7.1.26, flavokinaza, FK, RFK) je enzim sa sistematskim imenom ATP:riboflavin 5'-fosfotransferaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + riboflavin ADP + FMN

Kofaktori FMN i FAD učestvuju u brojnim procesima u svim organizmima, uključujući mitohondrijski elektronski transport, fotosintezu, masna-kiselinsku oksidaciju, i metabolizam vitamina B6, vitamina B12 i folata.

Reference[uredi - уреди | uredi izvor]

  1. Chassy, B.M., Arsenis, C. and McCormick, D.B. (1965). "The effect of the length of the side chain of flavins on reactivity with flavokinase". J. Biol. Chem. 240: 1338–1340. PMID 14284745. 
  2. Giri, K.V., Krishnaswamy, P.R. and Rao, N.A. (1958). "Studies on plant flavokinase". Biochem. J. 70: 66–71. PMID 13584303. 
  3. Kearney, E.B. (1952). "The interaction of yeast flavokinase with riboflavin analogues". J. Biol. Chem. 194: 747–754. PMID 14927668. 
  4. McCormick, D.B. and Butler, R.C. (1962). "Substrate specificity of liver flavokinase". Biochim. Biophys. Acta 65: 326–332. 
  5. Sandoval, F.J. and Roje, S. (2005). "An FMN hydrolase is fused to a riboflavin kinase homolog in plants". J. Biol. Chem. 280: 38337–38345. PMID 16183635. 
  6. Solovieva, I.M., Tarasov, K.V. and Perumov, D.A. (2003). "Main physicochemical features of monofunctional flavokinase from Bacillus subtilis". Biochemistry (Mosc) 68: 177–181. PMID 12693963. 
  7. Solovieva, I.M., Kreneva, R.A., Leak, D.J. and Perumov, D.A. (1999). "The ribR gene encodes a monofunctional riboflavin kinase which is involved in regulation of the Bacillus subtilis riboflavin operon". Microbiology 145: 67–73. PMID 10206712. 

Literatura[uredi - уреди | uredi izvor]

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