Renila-luciferin 2-monooksigenaza
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Renila-luciferin 2-monooksigenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.13.12.5 | ||||||||
CAS broj | 61869-41-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Renila-luciferin 2-monooksigenaza (EC 1.13.12.5, luciferaza Renilla tipa, aequorin, luciferaza (Renilla luciferin)) je enzim sa sistematskim imenom Renilla-luciferin:kiseonik 2-oksidoreduktaza (dekarboksilacija).[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Renilla luciferin + O2 oksidovani Renilla luciferin + CO2 + hnu
Ovaj enzim je izolovan iz mekog korala Renilla reniformis.
Reference[uredi | uredi kod]
- ↑ Cormier, M.J., Hori, K. and Anderson, J.M. (1974). „Bioluminescence in coelenterates”. Biochim. Biophys. Acta 346: 137-164. PMID 4154104.
- ↑ Hori, K., Anderson, J.M., Ward, W.W. and Cormier, M.J. (1975). „Renilla luciferin as the substrate for calcium induced photoprotein bioluminescence. Assignment of luciferin tautomers in aequorin and mnemiopsin”. Biochemistry 14: 2371-2376. PMID 237531.
- ↑ Shimomura, O. and Johnson, F.H. (1975). „Chemical nature of bioluminescence systems in coelenterates”. Proc. Natl. Acad. Sci. USA 72: 1546-1549. PMID 236561.
- ↑ Charbonneau, H. and Cormier, M.J. (1979). „Ca2+-induced bioluminescence in Renilla reniformis. Purification and characterization of a calcium-triggered luciferin-binding protein”. J. Biol. Chem. 254: 769-780. PMID 33174.
- ↑ Anderson, J.M., Charbonneau, H. and Cormier, M.J. (1974). „Mechanism of calcium induction of Renilla bioluminescence. Involvement of a calcium-triggered luciferin binding protein”. Biochemistry 13: 1195-1200. PMID 4149963.
- ↑ Lorenz, W.W., McCann, R.O., Longiaru, M. and Cormier, M.J. (1991). „Isolation and expression of a cDNA encoding Renilla reniformis luciferase”. Proc. Natl. Acad. Sci. USA 88: 4438-4442. PMID 1674607.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.