Rastvorna hinoproteinska glukozna dehidrogenaza
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| Rastvorna hinoproteinska glukozna dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.99.35 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Rastvorna hinoproteinska glukozna dehidrogenaza (EC 1.1.99.35, rastvorna glukozna dehidrogenaza, sGDH, glukozna dehidrogenaza (PQQ-zavisna)) je enzim sa sistematskim imenom D-glukoza:akceptor oksidoreduktaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-glukoza + akceptor D-glukono-1,5-lakton + redukovani akceptor
Ovaj rastvorni periplazmični enzim sadrži PQQ prostetičku grupu, koja je vezana za jon kalcijuma. Elektronski akceptor nije poznat.
Reference[uredi | uredi kod]
- ↑ Geiger, O. and Gorisch, H. (1986). „Crystalline quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus”. Biochemistry 25: 6043-6048.
- ↑ Dokter, P., Frank, J. and Duine, J.A. (1986). „Purification and characterization of quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus L.M.D. 79.41”. Biochem. J. 239: 163-167. PMID 3800975.
- ↑ Cleton-Jansen, A.M., Goosen, N., Wenzel, T.J. and van de Putte, P. (1988). „Cloning of the gene encoding quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus: evidence for the presence of a second enzyme”. J. Bacteriol. 170: 2121-2125. PMID 2834325.
- ↑ Matsushita, K., Shinagawa, E., Adachi, O. and Ameyama, M. (1989). „Quinoprotein D-glucose dehydrogenase of the Acinetobacter calcoaceticus respiratory chain: membrane-bound and soluble forms are different molecular species”. Biochemistry 28: 6276-6280. PMID 2551369.
- ↑ Oubrie, A. and Dijkstra, B.W. (2000). „Structural requirements of pyrroloquinoline quinone dependent enzymatic reactions”. Protein Sci. 9: 1265-1273. PMID 10933491.
- ↑ Matsushita, K., Toyama, H., Ameyama, M., Adachi, O., Dewanti, A. and Duine, J.A. (1995). „Soluble and membrane-bound quinoprotein D-glucose dehydrogenases of the Acinetobacter calcoaceticus : the binding process of PQQ to the apoenzymes”. Biosci. Biotechnol. Biochem. 59: 1548-1555.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.