Raksibakumab
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| Klinički podaci | |
|---|---|
| AHFS/Drugs.com | Monografija |
| Identifikatori | |
| CAS broj | 565451-13-0 |
| ATC kod | nije dodeljen |
| DrugBank | DB08902 |
| Hemijski podaci | |
| Formula | C6320H9794N1702O1998S42 |
| Mol. masa | 142.93 |
| Farmakokinetički podaci | |
| Poluvreme eliminacije | 15-19 dana |
| Farmakoinformacioni podaci | |
| Trudnoća | ? |
| Pravni status | |
| Način primene | Intravenozno |
Raksibakumab[1] je ljudsko monoklonalno antitelo namenjeno profilaksnoj primeni i lečenju udahnutog antraksa.[2][3][4] Njegova efikasnost je porvđena na zečevima i majmunima.[5]
Reference[uredi | uredi kod]
- ↑ Mazumdar, Sohini (2009). „Raxibacumab”. MAbs 1 (6): 531–538. DOI:10.4161/mabs.1.6.10195. PMC 2791309. PMID 20068396.
- ↑ Mazumdar S: Raxibacumab. MAbs. 2009 Nov-Dec;1(6):531-8. Epub 2009 Nov 29. PMID 20068396
- ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. DOI:10.1093/nar/gkq1126. PMC 3013709. PMID 21059682.
- ↑ David S. Wishart, Craig Knox, An Chi Guo, Dean Cheng, Savita Shrivastava, Dan Tzur, Bijaya Gautam, and Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. DOI:10.1093/nar/gkm958. PMC 2238889. PMID 18048412.
- ↑ Migone, TS; Subramanian, GM; Zhong, J; Healey, LM; Corey, A; Devalaraja, M; Lo, L; Ullrich, S i dr.. (2009). „Raxibacumab for the treatment of inhalational anthrax”. The New England Journal of Medicine 361 (2): 135–44. DOI:10.1056/NEJMoa0810603. PMID 19587338.
Literatura[uredi | uredi kod]
- Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10 izd.). New York: McGraw-Hill. DOI:10.1036/0071422803. ISBN 0-07-135469-7.
- Thomas L. Lemke, David A. Williams, ur. (2007). Foye's Principles of Medicinal Chemistry (6 izd.). Baltimore: Lippincott Willams & Wilkins. ISBN 0-7817-6879-9.
