Proteinski trimer
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Proteinski trimer u biohemiji je makromolekularni kompleks formiran od tri, često ne-kovalentno vezana, makromolekula kao što su proteini ili nukleinske kiseline. Homo-trimer se formira od tri identična molekula, dok se hetero-trimer formira od tri različita makromolekula. Kolagen je primer homo-trimernog proteina.[3][4][5]
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- ↑ „Entrez Gene: PCNA proliferating cell nuclear antigen”.
- ↑ Bowman GD, O'Donnell M, Kuriyan J (2004). „Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex”. Nature 429 (6993): 724–30. DOI:10.1038/nature02585. PMID 15201901.
- ↑ Wyckoff, R.; Corey, R. & Biscoe, J. (1935). „X-ray reflections of long spacing from tendon”. Science 82 (2121): 175–176. DOI:10.1126/science.82.2121.175. PMID 17810172.
- ↑ Clark, G.; Parker, E.; Schaad, J. & Warren, W. J. (1935). „New measurements of previously unknown large interplanar spacings in natural materials”. J. Amer. Chem. Soc 57 (8): 1509. DOI:10.1021/ja01311a504.
- ↑ Di Lullo, Gloria A.; Sweeney, Shawn M.; Körkkö, Jarmo; Ala-Kokko, Leena & San Antonio, James D. (2002). „Mapping the Ligand-binding Sites and Disease-associated Mutations on the Most Abundant Protein in the Human, Type I Collagen”. Journal of Biological Chemistry 277 (6): 4223–4231. DOI:10.1074/jbc.M110709200. PMID 11704682.