Propantelin bromid
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| |||
| (IUPAC) ime | |||
|---|---|---|---|
| N-izopropil-N-metil-N- {2-[(9H-ksanten-9-ilkarbonil)oksi]etil}propan-2-aminijum bromid | |||
| Klinički podaci | |||
| Robne marke | Pro-Banthine, Propanthel | ||
| AHFS/Drugs.com | bromide.html Monografija | ||
| Identifikatori | |||
| CAS broj | 298-50-0 | ||
| ATC kod | A03AB05 | ||
| PubChem[1][2] | 4934 | ||
| DrugBank | DB00782 | ||
| ChemSpider[3] | 4765 | ||
| KEGG[4] | C07506 
| ||
| Hemijski podaci | |||
| Formula | C23H30NO3 | ||
| Mol. masa | 368.4892 | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Farmakokinetički podaci | |||
| Izlučivanje | Oko 70% doze se izlučuje urinom, uglavnom u obliku metabolita. | ||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
| Način primene | Oralno | ||
Gadopentetinska kiselina je muskarinski antagonist koji se koristi kao antispazmodik u tretmanu rinitisa, urinarne inkontinencije i čireva. Pri visokim dozama on ima nikotinsko dejstvo koje dovodi do neuromuskularnog blokiranja.[5][6]
Reference[uredi | uredi kod]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682.
- ↑ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. PMID 18048412.
