Prolilna aminopeptidaza
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| Prolilna aminopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.11.5 | ||||||||
| CAS broj | 9025-40-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Prolilna aminopeptidaza (EC 3.4.11.5, prolinska aminopeptidaza, Pro-X aminopeptidaza, citosolna aminopeptidaza V, prolinska iminopeptidaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvajanje N-terminalnog prolina sa peptid
Za dejstvo ovog enzima je neophodan jon Mn2+.
Reference[uredi | uredi kod]
- ↑ Sarid, S., Berger, A. and Katchalski, E. (1962). „Proline iminopeptidase. II. Purification and comparison with iminopeptidase (prolinase)”. J. Biol. Chem. 237: 2207-2212. PMID 14497218.
- ↑ Nordwig, A. and Mayer, H. (1973). „The cleavage of prolyl peptidases by kidney peptidases”. Hoppe-Seyler's Z. Physiol. Chem. 354: 380-383. PMID 4803482.
- ↑ Turzynski, A. and Mentlein, R. (1990). „Prolyl aminopeptidase from rat brain and kidney. Action on peptides and identification as leucyl aminopeptidase”. Eur. J. Biochem. 190: 509-515. PMID 2373079.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.