Prolilna oligopeptidaza
(Preusmjereno sa stranice Prolil-oligopeptidaza)
| Prolilna oligopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.21.26 | ||||||||
| CAS broj | 72162-84-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Prolilna oligopeptidaza (EC 3.4.21.26, enzim postprolinskog odvajanja, prolinsko specifična endopeptidaza, postprolinska endopeptidaza, prolinska endopeptidaza, endoprolilpeptidaza, prolilna endopeptidaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza -Pro- i u manjoj meri -Ala- u oligopeptidima
Ovaj enzim je prisutan u povrću i flavobakterijama.
- ↑ Walter, R. and Yoshimoto, T. (1978). „Postproline cleaving enzyme: kinetic studies of size and stereospecificity of its active site”. Biochemistry 17: 4139-4144. PMID 708698.
- ↑ Nomura, K. (1986). „Specificity of prolyl endopeptidase”. FEBS Lett. 209: 235-237. PMID 3539636.
- ↑ Moriyama, A., Nakanishi, M. and Sasaki, M. (1988). „Porcine muscle prolyl endopeptidase and its endogenous substrates”. J. Biochem. (Tokyo) 104: 112-117. PMID 2851585.
- ↑ Rennex, D., Hemmings, B.A., Hofsteenge, J. and Stone, S.R. (1991). „cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue”. Biochemistry, 30: 2195-2203. PMID 1900195.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.