Pomoćna komponenta proteinaza
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| Pomoćna komponenta proteinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.45 | ||||||||
| CAS broj | 124566-20-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Pomoćna komponenta proteinaza (EC 3.4.22.45, HC-Pro) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Hidroliza Gly-Gly veze na svom C-terminusu, obično u sekvenci -Tyr-Xaa-Val-Gly-Gly. Takođe hidroliza potiviralnih poliproteina
Ovaj enzim kodiraju mnogi potivirusi.
Reference[uredi | uredi kod]
- ↑ Kasschau, K.D. and Carrington, J.C. (1995). „Requirement for HC-Pro processing during genome amplification of tobacco etch potyvirus”. Virology 209: 268-273. PMID 7747479.
- ↑ Verchot, J. (1998). „Potyvirus helper component proteinase”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 677-679.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Verchot, J. (1998). „Potyvirus helper component proteinase”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 677-679.