Heparozan-N-sulfat-glukuronatna 5-epimeraza
(Preusmjereno sa stranice Poli((1-4)-beta-D-glukuronasil-(1-4)-N-sulfo-alfa-D-glukozaminil) glukurona-5-epimeraza)
| Heparozan-N-sulfat-glukuronatna 5-epimeraza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 5.1.3.17 | ||||||||
| CAS broj | 112567-86-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Heparozan-N-sulfat-glukuronatna 5-epimeraza (EC 5.1.3.17, heparozanska epimeraza, heparosan-N-sulfat-D-glukuronazil 5-epimeraza, C-5 uronozilna epimeraza, poliglukuronatna epimeraza, D-glukuronilna C-5 epimeraza, poli((1,4)-beta-D-glukuronazil-(1,4)-N-sulfo-alfa-D-glukozaminil) glukurona-5-epimeraza) je enzim sa sistematskim imenom poli((1->4)-beta-D-glukuronasil-(1->4)-N-sulfo-alfa-D-glukozaminil) glukurona-5-epimeraza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- heparozan-N-sulfat D-glukuronat heparozan-N-sulfat L-iduronat
Ovaj enzim deluje na D-glukuronazilne ostatke susedne sa sulfatisanim D-glukozaminskim jedinicama u heparinskom prekursoru.
- ↑ Jacobsson, I., Bäckström, G., Höök, M., Lindahl, U., Feingold, D.S., Malmström, A. and Rodén, L. (1979). „Biosynthesis of heparin. Assay and properties of the microsomal uronosyl C-5 epimerase”. J. Biol. Chem. 254: 2975-2982. PMID 107165.
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