Piruvat oksidaza (KoA-acetilacija)
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| Piruvat oksidaza (KoA-acetilacija) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.2.3.6 | ||||||||
| CAS broj | 62213-57-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Piruvat oksidaza (KoA-acetilacija) (EC 1.2.3.6, piruvatna oksidaza (KoA-acetilacija)) je enzim sa sistematskim imenom piruvat:kiseonik 2-oksidoreduktaza (KoA-acetilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- piruvat + KoA + O2 acetil-KoA + CO2 +H2O2
Ovaj enzim je flavoprotein (FAD). On može da bude identičan sa EC 1.2.7.1, piruvat sintazom.
Reference[uredi | uredi kod]
- ↑ Reeves, R.E., Warren, L.G., Susskind, B. and Lo, H.-S. (1977). „An energy-conserving pyruvate-to-acetate pathway in Entamoeba histolytica. Pyruvate synthase and a new acetate thiokinase”. J. Biol. Chem. 252: 726-731. PMID 13076.
- ↑ Takeuchi, T., Weinbach, E.C. and Diamond, L.S. (1975). „Pyruvate oxidase (CoA acetylating) in Entamoeba histolytica”. Biochem. Biophys. Res. Commun. 65: 591-596. PMID 167776.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.