(Piruvat dehidrogenaza (acetil-transfer prsten))-fosfataza
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| (Piruvat dehidrogenaza (acetil-transfer prsten))-fosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.3.43 | ||||||||
| CAS broj | 9073-70-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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(Piruvat dehidrogenaza (acetil-transfer prsten))-fosfataza (EC 3.1.3.43, piruvat dehidrogenazna fosfataza, fosfopiruvat dehidrogenazna fosfataza, (piruvat dehidrogenaza (lipoamid))-fosfataza, (piruvat dehidrogenaza (lipoamid))-fosfat fosfohidrolaza) je enzim sa sistematskim imenom (piruvat dehidrogenaza (acetil-transfer))-fosfat fosfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- [piruvat dehidrogenaza (acetil-transfer)] fosfat + H2O [piruvat dehidrogenaza (acetil-transfer)] + fosfat
Ovaj mitohondrijski enzim je vezan sa EC 1.2.4.1, piruvat dehidrogenazom (acetil-transfer), u piruvat dehidrogenaznom kompleksu.
Reference[uredi | uredi kod]
- ↑ Linn, T.C., Pelley, J.W., Petit, F.H., Hucho, F., Randall, D.D. and Reed, L.J. (1972). „α-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart”. Arch. Biochem. Biophys. 148: 327-342. PMID 4401694.
- ↑ Reed, L.J., Damuni, Z. and Merryfield, M.L. (1985). „Regulation of mammalian pyruvate and branched-chain α-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation”. Curr. Top. Cell. Regul. 27: 41-49. PMID 3004826.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.