Pirimidinski-5'-nukleotidna nukleozidaza
(Preusmjereno sa stranice Pirimidinski-5'-nukleotid nukleozidaza)
Pirimidinski-5'-nukleotidna nukleozidaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.2.2.10 | ||||||||
CAS broj | 9023-31-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Pirimidinski-5'-nukleotidna nukleozidaza (EC 3.2.2.10, pirimidinko nukleotidna N-ribozidaza, Pyr5N) je enzim sa sistematskim imenom pirimidin-5'-nukleotidna fosforibo(dezoksiribo)hidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- pirimidin 5'-nukleotid + H2O D-riboza 5-fosfat + pirimidinska baza
Ovaj enzim takođe deluje na dUMP, dTMP i dCMP.
Reference[uredi | uredi kod]
- ↑ Imada, A. (1967). „Degradation of pyrimidine nucleotides by enzyme systems of Streptomyces. II. Pyrimidine 5′-nucleotide phosphoribo(deoxyribo) hydrolase of Streptomyces virginiae”. J. Gen. Appl. Microbiol. 13: 267-278.
- ↑ Imada, A., Kuno, M. and Igarasi, S. (1967). „Degradation of pyrimidine nucleotides by enzyme systems of Streptomyces. I. Ribose-5-phosphate formation from pyrimidine nucleotides”. J. Gen. Appl. Microbiol. 13: 255-265.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.