Peptidil-Asp metaloendopeptidaza
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| Peptidil-Asp metaloendopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.33 | ||||||||
| CAS broj | 55576-49-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Peptidil-Asp metaloendopeptidaza (EC 3.4.24.33, endoproteinaza Asp-N, peptidilna-Asp metaloproteinaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje Xaa-Asp, Xaa-Glu i Xaa-cisteinsko kiselinskih veza
Ovaj metaloenzim je izolovan iz Pseudomonas fragi.
Reference[uredi | uredi kod]
- ↑ Porzio, M.A. and Pearson, A.M. (1975). „Isolation of an extracellular neutral proteinase from Pseudomonas fragi”. Biochim. Biophys. Acta 384: 235-241. PMID 236771.
- ↑ Drapeau, G.R. (1980). „Substrate specificity of a proteolytic enzyme isolated from a mutant of Pseudomonas fragi”. J. Biol. Chem. 255: 839-840. PMID 7188696.
- ↑ Ingrosso, D., Fowler, A.V., Bleibaum, J. and Clarke, S. (1989). „Specificity of endoproteinase Asp-N (Pseudomonas fragi): cleavage at glutamyl residues in two proteins”. Biochem. Biophys. Res. Commun. 162: 1528-1534. PMID 2669754.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.