Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4
Prijeđi na navigaciju
Prijeđi na pretragu
| Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.115 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Peptidaza infektivnog pankreasnog nekroznog birnavirusa Vp4 (EC 3.4.21.115, proteaza virusa infektine pankreasne nekroze, IPNV Vp4 proteaza, IPNV Vp4 peptidaza, NS proteaza, NS-asocirana proteaza, Vp4 proteaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Presecanje (Ser/Thr)-Xaa-Ala-(Ser/Ala)-Gly motiva u poliproteinu NH2-pVP2-VP4-VP3-COOH infektinog pankreasnog nekroznog virusa na pVP2-VP4 i VP4-VP3 spojevima
Infektivni pankreasni nekrozni virus (IPNV) je birnavirus koji uzrokuje akutnu, zaraznu bolest kod mladih pastrmki.
Reference[uredi | uredi kod]
- ↑ Manning, D.S. and Leong, J.C. (1990). „Expression in Escherichia coli of the large genomic segment of infectious pancreatic necrosis virus”. Virology 179: 16-25. PMID 2219718.
- ↑ Petit, S., Lejal, N., Huet, J.C. and Delmas, B. (2000). „Active residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virus”. J. Virol. 74: 2057-2066. PMID 10666235.
- ↑ Dobos, P. (1995). „The molecular biology of infectious pancreatic necrosis virus (IPNV)”. Annu. Rev. Fish Dis. 5: 25-54.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.