Pankreasna endopeptidaza E
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| Pankreasna endopeptidaza E | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.70 | ||||||||
| CAS broj | 68073-27-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Pankreasna endopeptidaza E (EC 3.4.21.70, holestarol-vezujuća proteinaza, proteinaza E, holestarol-vezujuća serinska proteinaza, pankreasna proteaza E, pankreasna proteinaza E, holestarol-vezujuća pankreasna proteinaza, CBPP, pankreasna E proteinaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Preferentno razlaganje veze: Ala-. Ne dolazi do hidrolize elastina
Ova peptidaza iz S1 familije (tripsinske familije) je izolovan iz pankreasnog soka.
Reference[uredi | uredi kod]
- ↑ Mallory, P.A. and Travis, J. (1975). „Human pancreatic enzymes: purification and characterization of a nonelastolytic enzyme, protease E, resembling elastase”. Biochemistry 14: 722-729. PMID 234742.
- ↑ Shen, W., Fletcher, T.S. and Largman, C. (1987). „Primary structure of human pancreatic protease E determined by sequence analysis of the cloned mRNA”. Biochemistry 26: 3447-3452. PMID 3477287.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.