Oktreotid

Oktreotid
(IUPAC) ime
	(4R,7S,10S,13R,16S,19R)-19-[(2R)-2-amino-3-fenilpropanamido]-10-(4-aminobutil)-16-benzil-N-[(2R,3R)-1,3-dihidroksibutan-2-il]-7-(1-hidroksietil)-13-(1H-indol-3-ilmetil)-6,9,12,15,18-pentaokso-1,2-ditia-5,8,11,14,17-pentaazacikloikosan-4-karboksamid
Klinički podaci
Robne marke	Atrigel, Longastatin, Sandostatin, Sandostatin LAR
AHFS/Drugs.com	Monografija
Identifikatori
CAS broj	83150-76-9
ATC kod	H01CB02
DrugBank	DB00104
KEGG	C07306
Hemijski podaci
Formula	C49H66N10O10S2
Mol. masa	1019.239
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29?,34-,36+,37+,38-,39-,40+,41+,42+/m1/s1; Key: DEQANNDTNATYII-RRCPSWKPSA-N
Farmakokinetički podaci
Izlučivanje	Oko 32% se izlučuje nepromenjeno u urin.
Farmakoinformacioni podaci
Trudnoća	?
Pravni status
Način primene	Intramaskularno; Intravenozno

Oktreotid je acetatna so cikličnog oktapeptida. On je dugotrajni oktapeptid ima farmakološka svojstva koja oponašaju prirodni hormon somatostatin.^[2]^[3]^[4]

Reference[uredi - уреди | uredi izvor]

↑ Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Uhl W, Anghelacopoulos SE, Friess H, Buchler MW: The role of octreotide and somatostatin in acute and chronic pancreatitis. Digestion. 1999;60 Suppl 2:23-31. PMID 10207228
↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). "DrugBank 3.0: a comprehensive resource for omics research on drugs". Nucleic Acids Res. 39 (Database issue): D1035–41. PMID 21059682.
↑ Nucleic Acids Res (2008). "DrugBank: a knowledgebase for drugs, drug actions and drug targets" 36 (Database issue). pp. D901–6. PMID 18048412.

Spoljašnje veze[uredi - уреди | uredi izvor]

	Portal Medicina
	Portal Hemija

Octreotide

Molimo Vas, obratite pažnju na važno upozorenje u vezi tema o zdravlju (medicini).

[1] Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[2] Uhl W, Anghelacopoulos SE, Friess H, Buchler MW: The role of octreotide and somatostatin in acute and chronic pancreatitis. Digestion. 1999;60 Suppl 2:23-31. PMID 10207228

[3] Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). "DrugBank 3.0: a comprehensive resource for omics research on drugs". Nucleic Acids Res. 39 (Database issue): D1035–41. PMID 21059682.

[4] Nucleic Acids Res (2008). "DrugBank: a knowledgebase for drugs, drug actions and drug targets" 36 (Database issue). pp. D901–6. PMID 18048412.

[1]

[2]

[3]

[4]

Oktreotid

Reference[uredi - уреди | uredi izvor]

Spoljašnje veze[uredi - уреди | uredi izvor]

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