Oksepin-KoA hidrolaza
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| Oksepin-KoA hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.7.1.16 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Oksepin-KoA hidrolaza (EC 3.7.1.16, paaZ (gen)) je enzim sa sistematskim imenom 2-oksepin-2(3H)-ilideneacetil-KoA hidrolijaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2-oksepin-2(3H)-ilideneacetil-KoA + H2O 3-okso-5,6-dehidrosuberil-KoA semialdehid
Enzim iz bakterije Escherichia coli je bifunkcionalan fuzioni protein.
Reference[uredi | uredi kod]
- ↑ Ferrandez, A., Minambres, B., Garcia, B., Olivera, E.R., Luengo, J.M., Garcia, J.L. and Diaz, E. (1998). „Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway”. J. Biol. Chem. 273: 25974-25986. PMID 9748275.
- ↑ Park, S.J. and Lee, S.Y. (2003). „Identification and characterization of a new enoyl coenzyme A hydratase involved in biosynthesis of medium-chain-length polyhydroxyalkanoates in recombinant Escherichia coli”. J. Bacteriol. 185: 5391-5397. PMID 12949091.
- ↑ Ismail, W., El-Said Mohamed, M., Wanner, B.L., Datsenko, K.A., Eisenreich, W., Rohdich, F., Bacher, A. and Fuchs, G. (2003). „Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli”. Eur. J. Biochem. 270: 3047-3054. PMID 12846838.
- ↑ Teufel, R., Mascaraque, V., Ismail, W., Voss, M., Perera, J., Eisenreich, W., Haehnel, W. and Fuchs, G. (2010). „Bacterial phenylalanine and phenylacetate catabolic pathway revealed”. Proc. Natl. Acad. Sci. USA 107: 14390-14395. PMID 20660314.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.