O-1125

O-1125
(IUPAC) ime
	6-[(6aR,10aR)-1-hidroksi-6,6,9-trimetil-6a,7,10,10a-tetrahidrobenzo[c]hromen-3-il]-N,N,6-trimetilheptanamid
Klinički podaci
Identifikatori
ATC kod	nije dodeljen
PubChem	9909689
Hemijski podaci
Formula	C26H39NO3
Mol. masa	413,591 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C26H39NO3/c1-17-11-12-20-19(14-17)24-21(28)15-18(16-22(24)30-26(20,4)5)25(2,3)13-9-8-10-23(29)27(6)7/h11,15-16,19-20,28H,8-10,12-14H2,1-7H3 ; Key: QGBHDXFADXCURB-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

O-1125 (3-(1,1-dimetilheksil-6-dimetilkarboksamid)-Δ8-tetrahidrokanabinol) je lek koji je kanabinoidni derivat. On manifestuje analgetska svojstva i koristi se u naučnim istraživanjima. O-1125 je potentan CB₁ pun agonist sa Ki vrednošću od 1,16 nM.^[3]

Reference[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. 1999 Oct;128(3):684-8. DOI:10.1038/sj.bjp.0702806 PMID 10516649

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[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. 1999 Oct;128(3):684-8. DOI:10.1038/sj.bjp.0702806 PMID 10516649

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O-1125

Reference[uredi | uredi kod]

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