Nukleozid-trifosfataza
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| Nukleozid-trifosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.1.15 | ||||||||
| CAS broj | 9075-51-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Nukleozid-trifosfataza (EC 3.6.1.15, nukleozidna trifosfatna fosfohidrolaza, nukleozid-5-trifosfatna fosfohidrolaza, nukleozidna 5-trifosfataza) je enzim sa sistematskim imenom nespecifična difosfat fosfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- NTP + H2O NDP + fosfat
Ovaj enzim takođe hidrolizuje druge nukleozidne trifosfate, difosfate, tiamin difosfat i FAD.
Reference[uredi | uredi kod]
- ↑ Brightwell, R. and Tappel, A.L. (1968). „Lysosomal acid pyrophosphatase and acid phosphatase”. Arch. Biochem. Biophys. 124: 333-343. PMID 5661608.
- ↑ Lewis, M. and Weissman, S. (1965). „Properties of a soluble nucleoside triphosphatase activity in mammalian liver”. Arch. Biochem. Biophys. 109: 490-498. PMID 14320490.
- ↑ Matsushita, S. and Raacke, I.D. (1968). „Purification of nucleoside triphosphatases from pea seedling ribosomes”. Biochim. Biophys. Acta 166: 707-710. PMID 4301913.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.