Nukleotidna difosfataza
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| Nukleotid difosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.1.9 | ||||||||
| CAS broj | 9032-64-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Nukleotid difosfataza (EC 3.6.1.9, nukleotidna pirofosfataza, nukleotid-šećerna pirofosfataza) je enzim sa sistematskim imenom dinukleotid nukleotidohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- dinukleotid + H2O 2 mononukleotida
Supstrati su: NAD+, NADP+, FAD, KoA, kao i ATP i ADP.
Reference[uredi | uredi kod]
- ↑ Jacobson, J.B. and Kaplan, N.O. (1957). „A reduced pyridine nucleotide pyrophosphatase”. J. Biol. Chem. 226: 427-437. PMID 13428775.
- ↑ Kornberg, A. and Pricer, W.E. (1950). „Nucleotide pyrophosphatase”. J. Biol. Chem. 182: 763-778.
- ↑ Kumar, S.A., Rao, N.A. and Vaidyanathan, C.S. (1965). „Nucleotidases in plants. I. Partial purification and properties of the enzyme hydrolyzing flavine adenine dinucleotide from mung bean seedlings (Phaseolus radiatus)”. Arch. Biochem. Biophys. 111: 646-652. PMID 5862212.
- ↑ Swartz, M.N., Kaplan, N.O. and Lamborg, M.F. (1958). „A' "heat-activated" diphosphopyridine nucleotide pyrophosphatase from Proteus vulgaris”. J. Biol. Chem. 232: 1051-1063. PMID 13549486.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.