Norfenefrin
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| |||
| (IUPAC) ime | |||
|---|---|---|---|
| 3-(2-amino-1-hidroksietil)fenol | |||
| Klinički podaci | |||
| AHFS/Drugs.com | Internacionalno ime leka | ||
| Identifikatori | |||
| CAS broj | 536-21-0 15308-34-6 (hidrohlorid) | ||
| ATC kod | C01CA05 | ||
| PubChem[1][2] | 4538 | ||
| ChemSpider[3] | 4379 | ||
| UNII | D2P3M6SRN5 
| ||
| KEGG[4] | D08286
| ||
| ChEMBL[5] | CHEMBL358040
| ||
| Hemijski podaci | |||
| Formula | C8H11NO2 | ||
| Mol. masa | 153,178 g/mol | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Sinonimi | Norfenephrine Norphenephrine Norphenylephrine meta-Norsynephrine meta-Octopamine 3-Octopamine | ||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | ℞ Prescription only | ||
Norfenefrin (Coritat, Energona, Hypolind, Novadral, m-oktopamin, 3-oktopamin, 3,β-dihidroksifenetilamin) je adrenergički lek koji se koristi kao simpatomimetik. On je u prodaji u Evropi, Japanu, i Meksiku.[6][7] Zajedno sa strukturnim izomerima p-oktopaminom i tiraminom, norfenefrin je prirodni, endogeni trag amin. On deluje kao jedan od pomoćnih neurotransmitera u mozgu.[8]
Reference[uredi | uredi kod]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. str. 104. ISBN 978-0-412-46630-4.
- ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. str. 750. ISBN 978-3-88763-075-1. Pristupljeno 24. 4. 2012.
- ↑ Danielson TJ, Boulton AA, Robertson HA (December 1977). „m-Octopamine, p-octopamine and phenylethanolamine in rat brain: a sensitive, specific assay and the effects of some drugs”. Journal of Neurochemistry 29 (6): 1131–5. PMID 340613.
Literatura[uredi | uredi kod]
- Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. str. 750. ISBN 978-3-88763-075-1. Pristupljeno 24. 4. 2012.
- F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. str. 104. ISBN 978-0-412-46630-4.
