Neamin transaminaza
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| Neamin transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.93 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Neamin transaminaza (EC 2.6.1.93, glutamat---6'-dehidroparomamin aminotransferaza, btrB (gen), neoN (gen), kacL (gen)) je enzim sa sistematskim imenom neamin:2-oksoglutarat aminotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ova reakcija se odvija u reverznom smeru.
Reference[uredi | uredi kod]
- ↑ Huang, F., Spiteller, D., Koorbanally, N.A., Li, Y., Llewellyn, N.M. and Spencer, J.B. (2007). „Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin”. ChemBioChem. 8: 283-288. PMID 17206729.
- ↑ Clausnitzer, D., Piepersberg, W. and Wehmeier, U.F. (2011). „The oxidoreductases LivQ and NeoQ are responsible for the different 6′-modifications in the aminoglycosides lividomycin and neomycin”. J. Appl. Microbiol. 111: 642-651. PMID 21689223.
- ↑ Park, J.W., Park, S.R., Nepal, K.K., Han, A.R., Ban, Y.H., Yoo, Y.J., Kim, E.J., Kim, E.M., Kim, D., Sohng, J.K. and Yoon, Y.J. (2011). „Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation”. Nat. Chem. Biol. 7: 843-852. PMID 21983602.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.