Molibdopterin adenililtransferaza
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| Molibdopterin adenililtransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.75 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Molibdopterin adenililtransferaza (EC 2.7.7.75, MogA, Cnx1) je enzim sa sistematskim imenom ATP:molibdopterin adenililtransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + molibdopterin difosfat + adenilil-molibdopterin
Ovaj enzim katalizuje aktivaciju molibdopterina za molibdensko umetanje.
Reference[uredi | uredi kod]
- ↑ Nichols, J.D. and Rajagopalan, K.V. (2005). „In vitro molybdenum ligation to molybdopterin using purified components”. J. Biol. Chem. 280: 7817-7822. PMID 15632135.
- ↑ Kuper, J., Palmer, T., Mendel, R.R. and Schwarz, G. (2000). „Mutations in the molybdenum cofactor biosynthetic protein Cnx1G from Arabidopsis thaliana define functions for molybdopterin binding, molybdenum insertion, and molybdenum cofactor stabilization”. Proc. Natl. Acad. Sci. USA 97: 6475-6480. PMID 10823911.
- ↑ Llamas, A., Mendel, R.R. and Schwarz, G. (2004). „Synthesis of adenylated molybdopterin: an essential step for molybdenum insertion”. J. Biol. Chem. 279: 55241-55246. PMID 15504727.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.