Mitohondrijalna intermedijarna peptidaza
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| Mitohondrijalna intermedijarna peptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.59 | ||||||||
| CAS broj | 136447-30-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Mitohondrijalna intermedijarna peptidaza (EC 3.4.24.59, proteinaza transformacije mitohondrijskog intermedijernog prekursorA, MIP) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje N-terminalnog oktapeptida kao sekondni stupanj transformacije pojedinih proteina unesenih u mitohondrije
Ovaj enzim je homolog timetne oligopeptidaze.
Reference[uredi | uredi kod]
- ↑ Isaya, G., Kalousek, F. and Rosenberg, L.E. (1992). „Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase”. J. Biol. Chem. 267: 7904-7910. PMID 1560019.
- ↑ Isaya, G., Kalousek, F. and Rosenberg, L.E. (1992). „Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue”. Proc. Natl. Acad. Sci. USA 89: 8317-8321. PMID 1518864.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.