Metilentetrahidrometanopterin dehidrogenaza
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| Metilentetrahidrometanopterin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.99.9 | ||||||||
| CAS broj | 100357-01-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Metilentetrahidrometanopterin dehidrogenaza (EC 1.5.99.9, N5,N10-metilintetrahidrometanopterinska dehidrogenaza, 5,10-metilintetrahidrometanopterinska dehidrogenaza) je enzim sa sistematskim imenom 5,10-metilintetrahidrometanopterin:koenzim-F420 oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 5,10-metilintetrahidrometanopterin + koenzim F420 5,10-meteniltetrahidrometanopterin + redukovani koenzim F420
Ovaj enzim učestvuje u formiranju metana iz CO2 kod metanobakterija roda Thermoautotrophicum.
Reference[uredi | uredi kod]
- ↑ Hartzell, P.L., Zvilius, G., Escalante-Semerena, J.C. and Donnelly, M.I. (1985). „Coenzyme F420 dependence of the methylenetetrahydromethanopterin dehydrogenase of Methanobacterium thermoautotrophicum”. Biochem. Biophys. Res. Commun. 133: 884-890. PMID 4084309.
- ↑ te Brömmelstroet, B.W., Geerts, W.J., Keltjens, J.T., van der Drift, C. and Vogels, G.D. (1991). „Purification and properties of 5,10-methylenetetrahydromethanopterin dehydrogenase and 5,10-methylenetetrahydromethanopterin reductase, two coenzyme F420-dependent enzymes, from Methanosarcina barkeri”. Biochim. Biophys. Acta 1079: 293-302. PMID 1911853.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.